How Lorlatinib can Save You Time, Stress, and Money.
Hepatic biotransformation of MLN8054 was studied in vitro utilizing human liver S9 fractions (Data on file, Millennium). Glucuronidation from the carboxylate moiety of MLN8054 to an acyl glucuronide was the predominant system of biotransformation, Hydroxylation of your azepine moiety of MLN8054 was the main section one biotransformation pathway. Gl